I am Following the 2023 "Functional connectivity MRI quality control procedures in CONN" manuscript while performing some quality checks on my denoising proedure for two task-based datasets. I will noticed that my distributions of FC values are quite tall and narrow. I read this section of the paper I mentioned above that might explain why but I am not sure.
"No individual runs were identified as potential outliers
after
denoising from visual inspection of these results. Site #6
included
several runs with distinctive narrower FC distributions, but
these were
associated with scanning length that were considerably
longer
(identified in the Figure 9 DOF distribution as having
significantl
higher degrees of freedom compared to other runs in this
dataset)."
My two task-based datasets have 700 and 750 volumes both with a
TR of 0.8 seconds. Because of my TR value I am not low-pass
filtering and noticed that the FC distribution became much more
tall and narrow after setting the low-pass filter bound to 'Inf'. I
am only using WM and CSF CompCor components, 12 realignment
parameters, and scrubbing to denoise my data and the overall mean
of the FC distributions is very close to 0 for both of my datasets
(i.e., mean=0.005+-0.002 sd=0.053+=0.009 and mean=0.005+-0.002
sd=0.056+=0.008).
Any advice on if my tall, narrow FC distributions should cause me concern would be greatly appreciated!
