Dear Professor,
I am using CONN to perform a one-way ANOVA between three groups of subjects. When I performed an F-test (FWE control settings: voxel p<0.001 uncorrected; cluster p<0.05, FDR corrected), I obtained a significantly different region in the brain. However, when I tried to perform post-hoc comparisons using the same method,(The contrast matrix I set is [1 -1 0])I obtained three regions of difference.(the pictures are as below) The similar phenomenon sometimes results that the different region of post-hoc comparisons are larger than that of f test. This seems to indicate that I am getting some false-positive results. Should I adjust the p-value to avoid these false positives?if so ,how should I adjust?
looking foward to your reply
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Title | Author | Date |
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Junxiao Ma | Feb 1, 2025 | |
Alfonso Nieto-Castanon | Feb 9, 2025 | |