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help > RE: Using CONN in a block design task
Feb 11, 2012 06:02 AM | Alfonso Nieto-Castanon - Boston University
RE: Using CONN in a block design task
Hi Jiook,
I would possible start with Fair et al. 2007 manuscript (A method for using blocked and event-related fMRI data to study “resting state” functional connectivity). Other groups including ourselves have explored connectivity during task conditions (e.g. Whitfield-Gabrieli 2010, Associations and dissociations between default and self-reference networks in the human brain), but I do not know of any manuscript that have explicitly investigated the sensitivity of functional connectivity measures for different task-related design parameters. In general, and because of the typically low-frequency nature of the functional associations (at least those characteristic of resting state), I would probably recommend using relatively large blocks if possible (larger than the optimal ~15s blocks recommended for standard functional analyses), when exploring task-related functional connectivity measures.
Hope this helps
Alfonso
Originally posted by Juke Cha:
I would possible start with Fair et al. 2007 manuscript (A method for using blocked and event-related fMRI data to study “resting state” functional connectivity). Other groups including ourselves have explored connectivity during task conditions (e.g. Whitfield-Gabrieli 2010, Associations and dissociations between default and self-reference networks in the human brain), but I do not know of any manuscript that have explicitly investigated the sensitivity of functional connectivity measures for different task-related design parameters. In general, and because of the typically low-frequency nature of the functional associations (at least those characteristic of resting state), I would probably recommend using relatively large blocks if possible (larger than the optimal ~15s blocks recommended for standard functional analyses), when exploring task-related functional connectivity measures.
Hope this helps
Alfonso
Originally posted by Juke Cha:
Hi Alfonso,
I found that most of the refenreces for CONN are resting state studies.
I wonder if using this tool in a block design task has been validated. Is there any suggestion as to the requirement of study design (i.e., epoch lenght, iterations?) to get a maximum sensitivity of the data analysis using CONN?
Thanks,
Jiook
I found that most of the refenreces for CONN are resting state studies.
I wonder if using this tool in a block design task has been validated. Is there any suggestion as to the requirement of study design (i.e., epoch lenght, iterations?) to get a maximum sensitivity of the data analysis using CONN?
Thanks,
Jiook
Threaded View
| Title | Author | Date |
|---|---|---|
| Juke Cha | Jan 18, 2012 | |
| Alfonso Nieto-Castanon | Feb 11, 2012 | |