Hello,
I'm trying to perform a multisubject resting state analysis with CONN and I do the preprocessing with SPM. After coregistration of the functional data of each subjects with its structural image, i normalise with the MNI152_T1_2mm template and smooth. These preprocessed data I want to analyse in CONN. As far as i understood, I need a spatially normalised structural image for each subject in CONN.

What would happen if I used the MNI152 template as this strucural image for all subjects instead? Which information will  I loose or which confounds will be increased?  The reason I'm asking is that the segmentation of each structural image takes very long in comparison to performing just one segmentation for my whole analysis. Is there still a huge difference between the template and a structural image, which was normalised to this template?

Sorry, if this question sounds wrong or trivial, but I just started using SPM and CONN a few weeks ago.

Regards,

Felix