This repository contains a subset of a large-scale multi-vendor, multi-site collection of single-voxel MRS datasets that were acquired worldwide across 26 research sites on 3T MRI scanners from the three major vendors (GE, Philips, Siemens). Each site acquired up to 12 datasets.

Currently available data include (1) standard GABA+-edited MEGA-PRESS data, (2) macromolecule-suppressed GABA-edited MEGA-PRESS data, and (3) short-TE PRESS data.

If using these data, please cite:

Mikkelsen M et al. Big GABA: Edited MR spectroscopy at 24 research sites. NeuroImage 2017;159:32–45. doi: 10.1016/j.neuroimage.2017.07.021

Mikkelsen M et al. Big GABA II: Water-referenced edited MR spectroscopy at 25 research sites. NeuroImage 2019;191:537–548. doi: 10.1016/j.neuroimage.2019.02.059

Povazan M et al. Comparison of multivendor single-voxel MR spectroscopy data acquired in healthy brain at 26 sites. Radiology 2020;295:171–180. doi: 10.1148/radiol.2020191037

and acknowledge NIH grant R01 EB016089.