Wisconsin White Matter Hyperintensities Segmentation Toolbox

W2MHS is an open source MATLAB toolbox designed for detecting and quantifying White Matter Hyperintensities(WMH) in Alzheimer’s and aging related neurological disorders.Our toolbox provides a self-sufficient set of tools for segmenting these WMHs reliably and further quantifying their burden for down-processing studies. WMHs arise as bright regions on T2-weighted FLAIR images. They reflect comorbid neural injury or cerebral vascular disease burden. Their precise detection is of interest in Alzheimer’s disease (AD) with regard to its prognosis.

Please cite the following paper upon usage of this toolbox.
Ithapu, V., Singh, V., Lindner, C., Austin, B. P., Hinrichs, C., Carlsson, C. M., Bendlin, B. B. and Johnson, S. C. (2014), Extracting and summarizing white matter hyperintensities using supervised segmentation methods in Alzheimer's disease risk and aging studies. Hum. Brain Mapp.. doi: 10.1002/hbm.22472
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Specifications

License:Academic Free License ("AFL")
Domain:Computational Neuroscience
Programming Language:MATLAB
Supported Data Format:NIfTI-1
Other Keywords: alzheimer's, disease, hyperintensity, lesion, matter, white

Associations

execution requires:
SPM

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RE: Visualizing the result posted by Vamsi Ithapu on Mar 7

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RE: Visualizing the result posted by laura7 on Mar 7

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RE: Problem with image intensity? posted by Vamsi Ithapu on Mar 6

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RE: Problem with image intensity? posted by Vamsi Ithapu on Mar 6

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RE: Visualizing the result posted by Vamsi Ithapu on Mar 6

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Visualizing the result posted by laura7 on Feb 27

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Problem with image intensity? posted by laura7 on Feb 27

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RE: WMH map in the native FLAIR space posted by Vamsi Ithapu on Jan 19

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RE: WMH map in the native FLAIR space posted by Dan Wu on Jan 18

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RE: WMH map in the native FLAIR space posted by Vamsi Ithapu on Jan 17