Hi Alfonso,

Thanks for the quick response. We tried option 2, but we do have the problem that we require the 'set origin to (0,0,0)' option during preprocessing, otherwise SPM complains about to little overlap between scans during structural normalisation. How is this 'set origin' step performed? Is there a way to get the translation parameters? Because if we can apply it to the structural scan and then the same translation to our tissue maps prior to using CONN it should work with option 2.

Regards,
Jalmar