Dear Alfonso,

I am analysing a dataset of 6 participants (2 young adults, 2 old adults, 2 with Alzheimer's disease). The analysis is in native-space thus has used subject-specific ROIs. I just tried computing the second-level results and received an error, but I'm not quite sure what it means:

'ERROR DESCRIPTION:

Error using spm_check_orientations (line 65)
The orientations etc must be identical for this procedure.

Error in spm_spm (line 323)
spm_check_orientations(VY);

Error in conn_process (line 5008)
SPM=spm_spm(SPM);

Error in conn_process (line 60)
case 'results_voxel', [varargout{1:nargout}]=conn_process(16,varargin{:});

Error in conn (line 11497)
conn_process('results_voxel','readsingle','seed-to-voxel');

Error in conn (line 10649)
if state==2, conn gui_results_wholebrain;
CONN20.b
SPM12 + DAiSS DEM FieldMap MEEGtools
Matlab v.2020b
project: CONN20.b
storage: 3822.3Gb available'

In the command window there was the following:

'** The images do not all have same orientation and/or voxel sizes. **
The function assumes that a voxel in one image corresponds exactly
with the same voxel in another. This is not a safe assumption if
the orientation information in the headers or .mat files says that
the images are oriented differently. Please ensure that you process
all data correctly. For example, you may have realigned the images,
but not actually resliced them to be in voxel-wise alignment. 
Here are the orientation matrices of the image volumes. This list
can be used to determine which file(s) are causing the problem.

[-2 0 0 108; 0 1.8876 -0.661029 -70.6382; 0 0.661029 1.8876 -89.7196] /Volumes/My Passport for Mac/MSc Project/Pilot from 22.03/LC_rsfc_pilot_6sub_v1/results/firstlevel/6sub_v1/BETA_Subject001_Condition001_Source005.nii
[-2 0 0 108; 0 1.99011 -0.19864 -94.0521; 0 0.19864 1.99011 -73.6841] /Volumes/My Passport for Mac/MSc Project/Pilot from 22.03/LC_rsfc_pilot_6sub_v1/results/firstlevel/6sub_v1/BETA_Subject002_Condition001_Source005.nii
[-2 0 0 108; 0 1.96839 -0.354169 -88.8764; 0 0.354169 1.96839 -85.0559] /Volumes/My Passport for Mac/MSc Project/Pilot from 22.03/LC_rsfc_pilot_6sub_v1/results/firstlevel/6sub_v1/BETA_Subject003_Condition001_Source005.nii
[-2 0 0 108; 0 1.98754 -0.222938 -96.8922; 0 0.222938 1.98754 -77.5381] /Volumes/My Passport for Mac/MSc Project/Pilot from 22.03/LC_rsfc_pilot_6sub_v1/results/firstlevel/6sub_v1/BETA_Subject004_Condition001_Source005.nii
[-2 0 0 108; 0 1.85697 -0.742736 -78.8394; 0 0.742736 1.85697 -96.3385] /Volumes/My Passport for Mac/MSc Project/Pilot from 22.03/LC_rsfc_pilot_6sub_v1/results/firstlevel/6sub_v1/BETA_Subject005_Condition001_Source005.nii
[-2 0 0 108; 0 1.91261 -0.584743 -72.2799; 0 0.584743 1.91261 -97.2929] /Volumes/My Passport for Mac/MSc Project/Pilot from 22.03/LC_rsfc_pilot_6sub_v1/results/firstlevel/6sub_v1/BETA_Subject006_Condition001_Source005.nii'

Any help would be greatly appreciated.

Kind Regards,
Pavan