JHU–MNI single-subject atlas
The JHU–MNI single-subject atlas is a high-resolution, anatomically detailed neuroimaging atlas derived from a single human brain and spatially normalized to MNI stereotaxic space. The atlas was developed to provide a deterministic, anatomically sharp reference standard for brain MRI analysis, with a particular emphasis on white matter anatomy and tract-based parcellation.
Unlike population-averaged or probabilistic atlases, which blur anatomical boundaries due to inter-individual variability, the JHU–MNI single-subject atlas preserves true anatomical geometry, enabling precise localization, labeling, and visualization of brain structures. This design choice makes the atlas particularly well-suited for atlas-based quantification, diffusion MRI analysis, tract labeling, algorithm validation, and cross-study harmonization.
The atlas has been widely adopted in the neuroimaging community and serves as the anatomical foundation for multiple downstream resources used in structural and diffusion MRI research.
Unlike population-averaged or probabilistic atlases, which blur anatomical boundaries due to inter-individual variability, the JHU–MNI single-subject atlas preserves true anatomical geometry, enabling precise localization, labeling, and visualization of brain structures. This design choice makes the atlas particularly well-suited for atlas-based quantification, diffusion MRI analysis, tract labeling, algorithm validation, and cross-study harmonization.
The atlas has been widely adopted in the neuroimaging community and serves as the anatomical foundation for multiple downstream resources used in structural and diffusion MRI research.
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