The Mayo Clinic Adult Lifespan Template and its associated atlases were constructed and made publicly available to provide a template suitable for the analysis needs of aging and Alzheimer’s Disease population studies. Population-matched templates are known to allow more accurate quantitative MRI analysis, but most MRI standard templates are generated from scans of younger individuals. Unlike these, the MCALT is designed for analysis of MRI of adult subjects age 30+. MCALT was designed for use with SPM12 and integrates easily into its workflows, but is not specific to SPM12 and may be used easily with other segmentation software.
Funding: NIH U01 AG006786, NIH P50 AG016574, NIH R01 AG034676, NIH R01
AG011378, NIH R01 AG041851, NIH R01 NS097495, NIH R01 AG040042, GHR
Foundation, Elsie and Marvin Dekelboum Family Foundation, Alexander
Family Alzheimer's Disease Research Professorship of the Mayo
Clinic, Robert H. and Clarice Smith and Abigail van Buren Alzheimer
Disease Research Program, Liston Award, Schuler Foundation, Mayo
Foundation for Medical Education and Research