help > RE: Average within / between network connectivity
Apr 28, 2018  03:04 PM | Alfonso Nieto-Castanon - Boston University
RE: Average within / between network connectivity
Hi Himanshu,

Sorry for the late reply. Yes, that significant result can be directly reported and it means that there is a group effect in the between-networks connectivity (i.e. the average connectivity between the two networks is different among the groups). In addition, after getting a result like this, typically you would want to follow it up performing post-hoc analyses to better characterize those between-group differences (e.g. by performing a series of two-sample t-tests between pairs of groups; or you could plot the individual average between-network connectivity values for each group -e.g. by loading the "between-networks" column in the csv file as a new second-level covariate in conn so that you can use the tools.calculator gui there to plot those between-network connectivity values)

Hope this helps
Alfonso

Originally posted by Himanshu Joshi:
Hi Alfonso,

Thankyou for this wonderful script (conn_withinbeteenROItest). I have also used this script for exploring within and between network connectivity for three resting state networks; two networks at a time. I had four groups in my study and as per suggestions, using CONN's gui second-level results tab, ANOVA was implemented for between subjects contrast. After specifying the ANOVA model [1 -1 0 0; 0 1 -1 0; 0 0 1 -1] and selecting three networks in second level results tab, I ran the script "conn_withinbetweeROItest". This promted me to select, two networks which further resulted in

Within matrix Set-1 (4 x 4 ROIs; 12 valid ROI pairs; 99 subjects);
Within matrix Set-2 (7 x 7 ROIs; 42 valid ROI pairs; 99 subjects);
Between matrix (4 x 7 ROIs; 28 valid ROI pairs; 99 subjects;
Set-1 Within-network test (average effect between Set-1 ROIs):F(3 90 )=0.79 (p=0.505040)
Set-2 Within-network test (average effect between Set-2 ROIs): F(3 90 )=1.77 (p=0.159140)
Between-networks test (average effect between Set-1 & Set-2 ROIs):F(3 90 )=4.33; (p=0.006720).

The p-value for between network test was then converted into two-tailed p value: 2*min(p,1-p)= 0.0134.

Since the model specified here is ANOVA model, I was wondering, if we need to perform post-hoc tests. Or two tailed p value of 0.0134, which is significant, can be reported.

Thanks and Regards
Himanshu Joshi

Threaded View

TitleAuthorDate
Ruth Shaffer Apr 27, 2016
Alfonso Nieto-Castanon May 4, 2016
Chabran Eléna Sep 20, 2018
Maria Beser Feb 11, 2022
max345 Feb 1, 2022
Alfonso Nieto-Castanon Feb 3, 2022
max345 Feb 4, 2022
Alfonso Nieto-Castanon Feb 4, 2022
max345 Feb 9, 2022
max345 Feb 5, 2022
Himanshu Joshi Feb 16, 2018
RE: Average within / between network connectivity
Alfonso Nieto-Castanon Apr 28, 2018
Himanshu Joshi Apr 9, 2018
Himanshu Joshi Apr 28, 2018
Himanshu Joshi Mar 13, 2018
Himanshu Joshi Feb 26, 2018
Jon Dudley May 4, 2016
Alfonso Nieto-Castanon May 5, 2016
Helene Veenstra Feb 8, 2018
Alfonso Nieto-Castanon Feb 14, 2018
Helene Veenstra Feb 15, 2018
Stephen L. Feb 8, 2018
Helene Veenstra Feb 12, 2018
Mariah DeSerisy Apr 30, 2020
Elizabeth Olson May 16, 2020
Alfonso Nieto-Castanon May 19, 2020
Nadine Smith Feb 23, 2021
ryanw412 Dec 16, 2021
Jose Maximo Apr 28, 2021
Olivier Roy Oct 15, 2021
Karli Carston Nov 9, 2021