help > RE: Design matrix and contrast for 2 way ANOVA, and f-value
Jun 9, 2019  07:06 PM | Woomi Ban
RE: Design matrix and contrast for 2 way ANOVA, and f-value
Hi Dr.Zalesky,

Thanks for the quick answer and detail explanation.
It is very helpful to understand your tool. Base on your answer, I tried to find reference to other comments in the forum, but still have several questions.
Sorry for too many questions.

1. You suggested two different design before. My understanding is ...
1) For the main effect of Sex or Exposure,
I can use 1st design matrix and contrast will be [0 1/-1 0 0] for Sex and [0 0 1/-1 0] exposure.
Can I get the both main effect from the 2nd design matrix, too?
If so, how can I put the contrast for main effect of Exposure using the 2nd design matrix?

2) If I modeled 'The connectivity will be increased in Drug and Female', then which design is better?

2. t-test will return a one-sided p-value.
1) I'm trying to get significant level of data(p<0.05) using t-test.
Then, do I need to put 0.025 for Significance column in NBS tool for each independt test(contrast [0 0 0 1] or [0 0 0 -1])?

3. Threshold
1) When the t-value is calculated which factors are used for degree of freedom?
Is it include nummer of subjects and nodes? Or only number of subjects?

Thanks again!
Woomi

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TitleAuthorDate
Woomi Ban May 30, 2019
RE: Design matrix and contrast for 2 way ANOVA, and f-value
Woomi Ban Jun 9, 2019
Andrew Zalesky Jun 9, 2019
Andrew Zalesky May 31, 2019