help > RE: Design matrix and contrast for 2 way ANOVA, and f-value
Jan 21, 2020  11:01 AM | Andrew Zalesky
RE: Design matrix and contrast for 2 way ANOVA, and f-value
Hi David,

0 -1 0 0 means that group drug > group placebo ?
YES


0 0 -1 0 means that cond B > cond A ?

YES


0 0 0 -1 what would be here the meaning? How can I define this interaction?


The meaning of the interaction is no different to any other interaction term in a general linear model. The easiest way to understand the interaction is to visualize it.

Once again, I emphasize that the interaction term for the NBS is no different from any other interaction in a general linear model.

Andrew



Originally posted by davideit7:
Hi Dr. Zalesky,

eventually I've decided to use the design matrix below (2nd column treatment, 3rd condition, 4th interaction)

1-P_A 1  1  1  1

1-P_B 1  1 -1 -1

2-P_A 1  1  1  1

2-P_B 1  1 -1 -1

3-D_A 1 -1  1 -1

3-D_B 1 -1 -1  1

4-D_A 1 -1  1 -1

4-D_B 1 -1 -1  1

as you suggested I've used a t-test and separately used a contrast of 1 and -1, however I'm not sure about the meaning of the different contrasts:0 -1  0  0 means that group drug > group placebo ?

0  0 -1  0 means that cond B > cond A ?

0  0  0 -1 what would be here the meaning? How can I define this interaction?

Sincerly,

Davide

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Woomi Ban May 30, 2019
davideit7 Dec 5, 2019
Andrew Zalesky Dec 6, 2019
davideit7 Dec 6, 2019
Andrew Zalesky Dec 7, 2019
davideit7 Jan 20, 2020
RE: Design matrix and contrast for 2 way ANOVA, and f-value
Andrew Zalesky Jan 21, 2020
davideit7 Jan 22, 2020
Andrew Zalesky Jan 23, 2020
Woomi Ban Jun 10, 2019
Andrew Zalesky Jun 10, 2019
Andrew Zalesky Jun 1, 2019