help > RE: Design matrix and contrast for 2 way ANOVA, and f-value
Jan 20, 2020  02:01 PM | davideit7
RE: Design matrix and contrast for 2 way ANOVA, and f-value
Hi Dr. Zalesky,

eventually I've decided to use the design matrix below (2nd column treatment, 3rd condition, 4th interaction)

1-P_A 1  1  1  1

1-P_B 1  1 -1 -1

2-P_A 1  1  1  1

2-P_B 1  1 -1 -1

3-D_A 1 -1  1 -1

3-D_B 1 -1 -1  1

4-D_A 1 -1  1 -1

4-D_B 1 -1 -1  1

as you suggested I've used a t-test and separately used a contrast of 1 and -1, however I'm not sure about the meaning of the different contrasts:
0 -1  0  0 means that group drug > group placebo ?

0  0 -1  0 means that cond B > cond A ?

0  0  0 -1 what would be here the meaning? How can I define this interaction?

Sincerly,

Davide

Threaded View

TitleAuthorDate
Woomi Ban May 30, 2019
davideit7 Dec 5, 2019
Andrew Zalesky Dec 6, 2019
davideit7 Dec 6, 2019
Andrew Zalesky Dec 7, 2019
RE: Design matrix and contrast for 2 way ANOVA, and f-value
davideit7 Jan 20, 2020
Andrew Zalesky Jan 21, 2020
davideit7 Jan 22, 2020
Andrew Zalesky Jan 23, 2020
Woomi Ban Jun 10, 2019
Andrew Zalesky Jun 10, 2019
Andrew Zalesky Jun 1, 2019