Hi Dr. Zalesky

Thanks for this really usefull toolbox. I've just started to use it and I'm still quite insecure relatively to the definition of the design matrix.
I think this is the adeguate place to post my question.
I have 16 subjects equally divided in 2 groups (placebo & treatment) and each of the subjects participate in 2 different condition (inclusion & exclusion), I suppose I should design a 2 way between subjects anova.
I've define the design matrix and contrast that you can find attached, I'm wondering if this is correct or not. Furthermore I have some other question:

1- Should I also add a column of 1's as first column?
2- What would be better to use a t-test or an f-test?
3- How many permutation should I set?

Thanks for your attention.
Davide