Pre-Operative and post-Recurrence brain Tumor Registration (PORTR) is a software package designed for determining the optimal deformation between pre-operative and post-recurrence scans by finding the minimum of an energy function, which is based on the concept of symmetric registration.

Some typical applications of PORTR include:
- Mapping post-recurrence scans to pre-operative scans
- Labeling entire brain regions of each scan.

PORTR is implemented as a command-line tool. It is semi-automatic and requires minimal user initializations. Users could use the visual interface called CaPTk to easily make initializations and a script for the execution. As a result, PORTR will output a label map of each scan, a mapping between two scans, etc.

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